New gene-editing technique offers scientists ability to ‘turn on’ enzymes that cause DNA base mutations

3D-model of DNA. Credit: Michael Ströck/Wikimedia/ GNU Free Documentation License Targeted mutations to the genome can now be introduced by splitting specific mutator enzymes and then triggering them to reconstitute, according to research from the Perelman School of Medicine at the University of Pennsylvania. Led by graduate student Kiara Berríos under the supervision of Rahul Kohli, MD, Ph.D., an associate professor of Infectious Diseases at Penn, and Junwei Shi, Ph.D., an assistant professor of Cancer Biology, the investigations uncovered a novel gene editing technique that offers superior control compared to other existing techniques and has the potential to be used

Near total loss of historical lands leaves Indigenous nations in the US more vulnerable to climate change

Credit: Unsplash/CC0 Public Domain In a first-of-its-kind study, a team of researchers attempted to quantify the massive loss of historical lands by Indigenous nations across the United States since European settlers first began laying claim to the continent. They also found historical land dispossession was associated with current and future climate risks as Indigenous peoples were forced to lands that are more exposed to a range of climate change… Continue Reading News Source:

Increased cognitive demands offset low-back exoskeleton advantages, research finds

Credit: CC0 Public Domain In manufacturing, work-related lower-back injuries from lifting and handling heavy objects account for approximately $100 billion in medical bills annually in the United States, according to data from the Bureau of Labor Statistics. Although novel ergonomic interventions such as industrial exoskeletons have shown promise in reducing the risk of musculoskeletal injuries, new research finds that the cognitive fit (where the wearer has ample mental resources available to accurately operate the exoskeleton while conducting their daily work tasks) of such wearable robotic solutions in the workplace may impose newer risks on workers. … Continue Reading News Source:

New hydrogen storage material steps on the gas

View of a subnanoscale reversible alane cluster coordinated to a bipyridine site on covalent triazine-based framework that can be used in hydrogen storage systems. Credit: Lawrence Livermore National Laboratory Hydrogen is increasingly viewed as essential to a sustainable world energy economy because it can store surplus renewable power, decarbonize transportation and serve as a zero-emission energy carrier. However, conventional high-pressure or cryogenic storage pose significant technical and engineering challenges. … Continue Reading News Source:

Social mobility is influenced by where ancestors lived

Credit: Pixabay/CC0 Public Domain There are clear and enduring regional divides across Great Britain, finds an intergenerational assessment of the social mobility of British families between 1851 and 2016, carried out by University College London (UCL) researchers at the Consumer Data Research Centre (CDRC). Professor Paul Longley, Dr. Justin Van Dijk and Dr. Tian Lan (all of UCL Geography) created GB Names, which allows users to chart exactly where… Continue Reading News Source:

Juno spacecraft peers deep into Jupiter’s colorful belts and zones

Artist impression based on JunoCam image of Jupiter acquired on July 21, 2021. Enhanced to highlight features, clouds, colors, and the beauty of Jupiter. Credit: NASA / SwRI / MSSS / Tanya Oleksuik CC NC SA A University of Leicester study of data captured in orbit around Jupiter has revealed new insights into what’s happening deep beneath the gas giant’s distinctive and colorful bands. Data from the microwave radiometer carried by NASA’s Juno… Continue Reading News Source:

Research Suggests Bacteria & Fungi Interact Far More Than We Knew

Genomic sequencing tools have enabled researchers to study microbial communities that are everywhere in our world, even our bodies. The interactions between bacteria and other bacteria, and bacteria and the viruses that infect them are of particular interest to scientists studying human microbiomes or drug resistant infections, for example. A new study has assessed the interactions that can occur between bacteria and fungi. This work, reported in Communications Biology, revealed that fungal organisms can host a wide array of bacteria, and has dramatically expanded what we knew about the so-called fungal microbiome or mycobiome. “Until now, examples of bacterial-fungal interactions

What’s Causing the Mysterious Radio Waves Coming From the Heart of the Milky Way?

Artist’s impression of the oscillating, variable radio signal ASKAP J173608.2-321635 arriving at Earth from towards the center of the Milky Way. Credit: Sebastian Zentilomo/University of Sydney The center of the Milky Way is a mysterious place. Astronomers think there’s a supermassive black hole there, though it could be dark matter instead. The region is densely packed with stars, dominated by red giants. And because of all the dust between Earth and the galactic center, we can’t see anything with visible light, ultraviolet light, or low-energy x-rays. But we can detect radio waves, and there are some unexplained ones coming from

Could we make a superhuman?

Paul Atreides, the hero of Dune, discovers that he has been gifted with incredible, superhuman powers – such as precognition and omniscience. This is no accident. Paul is the result of painstaking genetic engineering and selective breeding over many generations by an organisation known as the Bene Gesserit. The question is: could you, in the real world, breed, or genetically edit, a ‘chosen one’? In November 2018, the world was shocked by news that the first gene-edited human babies had been born in China. According to He Jiankui, the rogue scientist behind the project, the twin girls’ genetic make-up had

Facebook rebrands as Meta to emphasize ‘metaverse’ vision

Seen on the screen of a device in Sausalito, Calif., Facebook CEO Mark Zuckerberg delivers the keynote address during a virtual event on Thursday, Oct. 28, 2021. Zuckerberg talked up his latest passion—creating a virtual reality “metaverse” for business, entertainment and meaningful social interactions. Credit: AP Photo/Eric Risberg Facebook CEO Mark Zuckerberg said his company is rebranding itself as Meta in an effort to encompass its virtual-reality vision for the future—what Zuckerberg calls the ” metaverse.” Skeptics point out that it also appears to be an… Continue Reading News Source: